Lorcaserin Review

Lorcaserin slimming pill

Do you want to lose a few kilograms fast by reducing your appetite?

Take Lorcaserin diet pills at least twice a day and they will help you to get rid of subcutaneous fat, lose belly fat, significantly reduce body weight in a fast pace.

Buying Lorcaserin, you choose one of the most effective diet pills available at the international market.

When using Lorcaserin, you will be able to quickly and safely:

  • Control the appetite throughout the day!
  • Increase the body’s ability to burn fat!
  • Achieve a very rapid weight loss!

Just two Lorcaserin 10mg diet pills per day are sufficient to significantly reduce BMI, body fat percentage and body weight within a few weeks.

These advantages make Lorcaserin pills ideal for use as a core of a successful weight loss program.

Herewith, it is important to be aware that not all appetite suppressants are the same, and Lorcaserin has several distinctive features.

It is because of these features, tens of thousands of obese Americans monthly choose Lorcaserin to combat obesity.

Lorcaserin is highly appreciated for its ability to safely and effectively:

1. Decrease appetite
2. Reduce sugar cravings
3. Induce feelings of fullness (satiety).

Ultimately, Lorcaserin helps decrease calorie consumption and very quickly reduce body fat.

Because these weight loss pills help to regulate hunger, they play a critical role in supporting weight loss efforts and maintaining a healthy metabolic function.

However, when thinking about weight loss, it is important to be aware that a calorie controlled diet and regular exercise are needed alongside the pills.

It’s the only way to quickly boost your metabolism and speed up the rate, at which your body burns calories and loses weight.

Earlier, for weight loss, you needed to take one 10 mg Lorcaserin pill twice a day.

A new dosage form – Lorcaserin 20mg with a sustained release of the anorexigenic agent Lorcaserin came into the market already in 2016.

Unlike Lorcaserin 10mg pills that should be taken twice a day, new Lorcaserin 20mg diet pills should be taken only once a day.

These diet pills are available for sake under the brand name Lorcaserin XR.

If you want to lose weight quickly, improve BMI and get a perfect figure in just a few months, order Lorcaserin drug today.

Unlike many other weight management products in the USA, these diet pills do not cause serious side effects.

About Belviq (Lorcaserin) diet pills

The lowest price of one Belviq (Lorcaserin) 10 mg tablet is $2.5 U.S.

Given that it is recommended to take two tablets daily, the cost of obesity treatment with this slimming drug is not less than $5 U.S. a day.

  • The minimum recommended treatment duration is 3 months.

Thus, costs for a course of anti-obesity therapy is not less than $450 USD.

High price of Lorcaserin tablets is due to huge funds invested in the development of their active ingredient.

However, under conditions of huge competition on the market of prescription anti-obesity drugs, Arena company will be forced to gradually reduce the price of pills.

It is not difficult to assume that within the next 5-7 years, the price for the drug will be compared to the price of the best-selling diet pills, Sibutramine and Phentermine.

After all, by 2020, dozens of Belviq generic drugs (Lorcaserin diet pills) will be available for sale, thus Arena Company will be forced to compete with dozens of different pharmaceutical companies.

It should be noted that Arena Pharmaceuticals already today provides potential buyers the possibility to save their money when buying these weight loss pills.

Potential buyers of anti-obesity drugs have the possibility to get absolutely free up to 30 weight loss pills, thus saving up to $75.

To get a coupon for free pills, you need to visit the website of Belviq (Lorcaserin) manufacturing company and to register savings card or voucher for the tablets.

You can find out from your treating physician the information how to get voucher or savings card for this anti-obesity medication.

Some online pharmacies also offer their visitors the possibility to buy Lorcaserin online at a low price.

However, you should always remember that the sale or purchase of these pills online without a prescription is illegal and prohibited.

So, before you buy Lorcaserin online, consult the treating physician, who will tell you about all legal ways to buy prescription anti-obesity drugs online.

If you have never taken this slimming medication, carefully study the list of side effects, recommended dosage and other important information.

It is quite possible that these pills are contraindicated to you, so you’d better use other prescription or OTC diet pills for obesity treatment.

Lorcaserin review

Lorcaserin Hydrochloride (INN: Lorcaserin) was approved by FDA on June 27, 2012.

In the US, this anti-obesity drug went on sale under trade name Belviq on June 11, 2013.

Oral tablets Belviq (Lorcaserin) 10mg are available at the US pharmaceutical market.

Arena Pharmaceuticals is the developer of the anti-obesity drug Lorcaserin and the right holder of the trade name Belviq.

Pills are produced at a factory in Switzerland.

Eisai Inc. company is a distributor of Belviq diet pills in the US.

Ildong Pharmaceutical carries out distribution of Lorcaserin diet pills in the South Korea, and CY Biotech – in Taiwan.

In 2013, Eisai Inc. was planning to obtain a license to sell Belviq (Lorcaserin) in Mexico, Canada and Brazil.

A patent for the invention of molecular formula Lorcaserin is valid until 2023.

In the US, Arena Pharmaceuticals plans to extend the patent term for Lorcaserin until 2026.

This means that the first Belviq generic drugs (diet pills containing Lorcaserin) will be sold in the US not earlier than in 2026-2027.

It should be noted that in May 2013, Arena Pharmaceuticals voluntarily withdrew its application from the EMA for getting license to sell Lorcaserin pills in EU.

Therefore, this anti-obesity drug is still not available at the European market of pharmaceutical products, and Lorcaserin is not available for sale in the UK.

How does Lorcaserin help to lose weight?

Lorcaserin is the active ingredient with a pharmacological property to activate serotonin 2C receptors (in the brain), which take part in appetite modulation.

The exact mechanism of Lorcaserin action is not fully understood.

However, it is known for certain that this active pharmaceutical ingredient helps to increase the satiety, thus reducing food consumption.

Whom diet pills containing Lorcaserin are prescribed for?

These pills are prescribed for people with excessive weight (BMI ≥ 27), as well as patients suffering from obesity (BMI ≥ 30).

Like any other anti-obesity drug, Lorcaserin should be taken in combination with a low-fat diet and increased physical activity.

Where can I buy Lorcaserin drug?

Lorcaserin pills are sold at city pharmacies by prescription only.

To get a prescription for Lorcaserin, you should see a doctor who will prescribe you a medical examination.

If the results of the medical examination confirm that you have no contraindications to use this drug, the doctor can issue a prescription.

If Lorcaserin is contraindicated in you, the doctor will prescribe other RX anti-obesity drugs (Phentermine, Diethylpropion, Sibutramine, Orlistat), or OTC diet pills (metabolism boosters, fat burners).

Lorcaserin in 2018

Tens of thousands of obese Americans use their health insurance to obtain free Lorcaserin diet pills.

Even more obese Americans buy Lorcaserin pills without insurance.

The supplier of Lorcaserin daily works to make the new Lorcaserin diet pills more affordable not only for obese Americans, but also for residents of other countries.

One of the countries where Lorcaserin pills were approved as an obesity treatment in 2015 in South Korea.

Before the start of Lorcaserin retail sales in South Korea, about 150 thousand of prescriptions were issued for these diet pills every quarter in the US.

The appearance of new Lorcaserin diet pills at the South Korean market promoted the growth of the global sales of the drug and the increase of profit of this anti-obesity drug manufacturer.

Just as it is in the US, in South Korea, Lorcaserin suppliers compete with the suppliers of other effective diet pills – Phentermine.

Therefore, competitive fight between the exclusive distributor of Lorcaserin and numerous distributors of Phentermine undoubtedly does affect the price of Lorcaserin in South Korea.

  • In the US, patent for Lorcaserin will expire in 2023.

If data of post-marketing studies demonstrates that Lorcaserin is more effective and safer than Phentermine-containing drugs, the manufacturers of Lorcaserin pills will occupy dominant positions at the global market of weight loss products within the next 8 years.

And a new study did prove that one of major dangers in the use of this drug, heart valve damage, was not confirmed in a large-scale study, and this news came in on August 26, 21018.

So, now it’s just a matter of time that the sales blossom.

What about the modified-release form of Lorcaserin?

Well…

Lorcaserin XR pills differ from Lorcaserin pills by a more extended anorexigenic effect.

Due to the prolonged anorexigenic activity, one dose of Lorcaserin XR is sufficient for an effective appetite control throughout the entire day.

Over 1Q 2018, Lorcaserin sales in the USA rose by 13.7% and reached 12.8 million USD.

Net sales of Lorcaserin in 1Q 2018 (in the US and South Korea) are 14 million USD.

Lorcaserin pills are actively promoted at the international pharmaceutical market.

Manufacturers and distributors of Lorcaserin

You already know that this anti-obesity medication is produces by the US biopharmaceutical company Arena.

Japanese pharmaceutical company Eisai is a distributor of Belviq (Lorcaserin) 10mg tablets in the USA, Canada, Mexico and Brazil.

Korean pharmaceutical company Ildong is a distributor of Belviq (Lorcaserin) 10 tablets in the South Korea.

Taiwanese pharmaceutical company CY Biotech is a distributor of Belviq (Lorcaserin) 10 tablets in Taiwan.

Lorcaserin contraindications

Lorcaserin has a small number of contraindications.

Although, the results of post-marketing studies may expand the list of contraindications for this anti-obesity drug.

These slimming pills should NOT be prescribed for obesity treatment in:

  • Pregnant women
  • Adolescents under 18 years
  • Patients with individual hypersensitivity to Lorcaserin
  • Patients with diagnosed serotonin syndrome.

Particular caution should be observed by patients who are going to use this drug together with other serotonergic drugs, such as:

  • SNRIs
  • SSRIs
  • TCAs
  • Triptans
  • Neuroleptics (Antipsychotics)
  • MAO inhibitors.

Before including Lorcaserin in combined drug therapy, it is important to carefully study the information about its drug interactions and (or) consult a health care professional.

Lorcaserin dosage

Optimal daily dose of the anti-obesity medication Lorcaserin is 20mg.

The total daily dose of Lorcaserin 20mg should be divided into 2 intakes.

Dosing time does not depend on meals.

To achieve the maximum therapeutic effect, it is recommended to take:

  • one Lorcaserin 10mg pill in the morning
  • one Lorcaserin 10mg pill in the afternoon.

OR

  • one extended-release Lorcaserin 20mg pill in the morning.

Keep in mind!

This slimming medication stimulates CNS and can cause insomnia.

So, even if you have night hunger, it is not recommended to take the pills in the evening.

Dosing regimen of Lorcaserin pills does not depend on the patient’s age, sex and race.

Change of Lorcaserin dosage may be required only when obesity treatment goes along pharmacological treatment of other diseases.

Before including slimming pills in a combined drug therapy course, doctor may prescribe an additional medical examination and diagnostic tests.

Keep in mind!

20mg is the maximum recommended dose of the drug.

Exceeding the daily dose may cause overdose.

The first symptoms of overdose are nausea, headache and dizziness.

In addition, high doses of Lorcaserin may cause hallucinations, motor activity and euphoria.

When overdose symptoms manifest, stop using Lorcaserin pills and ask for professional medical help.

If hemodialysis is required to treat overdose symptoms, the doctor may take a decision to hospitalize the patient.

Lorcaserin drug interactions

Lorcaserin increases the level of serotonin in the CNS and may enhance the pharmacological activity of other serotonergic drugs.

When using this weight loss med with other drugs increasing the level of serotonin in the CNS, serotonin syndrome may occur.

It is because of the high risk of serotonin syndrome, these diet pills are contraindicated in patients taking other serotonergic drugs.

In addition, Lorcaserin may enhance the pharmacological activity of medications that are Cytochrome P450 substrates.

Therefore, be sure to consult the treating physician before using this drug simultaneously with the mentioned medications.

Lorcaserin during pregnancy and breastfeeding

Like any other CNS stimulant, Lorcaserin is contraindicated in pregnant women.

Taking Lorcaserin pills during pregnancy or when planning the pregnancy, the woman endangers the health of her unborn child.

That is why, women should make sure that they are not pregnant before starting the slimming course with this drug.

  • Moreover, women of reproductive age should use reliable contraception methods.

Convincing data that Lorcaserin drug can pass into the breast milk has not yet been published.

However, nursing mothers are better to refrain from using this anti-obesity drug, because it may create a potential threat to the overall health of the newborn.

Lorcaserin side effects

The likelihood of side effects of Lorcaserin was studied during the long-term clinical studies.

About 9% of the total number of patients, involved in the clinical trials, had to stop taking Lorcaserin diet pills because of severe side effects.

The most common side effects, which require the immediate cessation of Lorcaserin pills, are:

  • Depression
  • Dizziness
  • Severe headache.

Severe side effects that have promoted the cessation of obesity drug therapy were reported in patients who took one Lorcaserin 10mg pill two times daily.

Approximately 5% of obese patients (without diabetes) experienced weak or moderate side effects (constipation, dry mouth, nausea, fatigue, dizziness, headache), which did not require immediate cessation of obesity drug therapy.

To prevent side effects, observe the interval between the doses of at least 6 hours, and do not exceed the highest recommended daily dose of 20mg.

Important information about Lorcaserin

If daily use of the maximum daily dose of Lorcaserin 20mg within 3 months has provided weight loss by less than 5% of the initial weight, the course of anti-obesity therapy should be discontinued.
When regular use of Lorcaserin pills does not provide a significant weight loss, one should discuss with the doctor the possibility to replace Lorcaserin with alternative diet pills.

Obese patients with severe cardiovascular diseases did not take part in clinical trials of Lorcaserin.

Therefore, if obesity is complicated by cardiovascular risk factors, Lorcaserin pills should be taken under the doctor’s supervision.

However, the mentioned recent study of the drug safety for the heart valves has slightly changed the overall image of the drug use in cardiac patients.

In some patients, this drug causes drowsiness.

So, before you engage in driving or operating machinery, make sure that the drug does not worsen cognitive functions.

If depression symptoms are observed in obese person, these symptoms may worsen after the start of the drug treatment for obesity.

In addition, this medication may contribute to suicide thoughts in obese patients with depression.

If the signs of suicidal behavior are observed after the start of obesity drug therapy, stop taking Lorcaserin diet pills.

  • Along with weight loss, blood sugar level may decrease, thus causing hypoglycemia.

So, diabetic patients on Lorcaserin pills should control blood sugar level and change the dosing regimen of anti-diabetic medications, if needed.

Spontaneous painful erection lasting more than 6 hours (priapism) may occur in men on Lorcaserin.

Men predisposed to priapism (for example, men with myeloma) should take these diet pills with caution.

Men with anatomical deformation of the penis, as well as men taking medications for erectile dysfunction treatment (Stendra, Cialis, Viagra, Levitra) should be very careful while using these slimming pills.

Lorcaserin and Phentermine

Several years after the start of Lorcaserin retail sales, Arena Pharma announced the launch of new clinical trials of Lorcaserin.

New trials were held involving a partner of Arena Pharma – Eisai Company.

The purpose of new trial was to study the safety of combined use of Lorcaserin tablets and Phentermine anorectic drug.

These clinical trials involved about 225 adults suffering from excessive weight or obesity.

  • Synergistic effect of Lorcaserin and Phentermine has been studied within 12 weeks.

During the trials, scientists studied the pharmacokinetic properties of Lorcaserin 10mg and Phentermine 15mg doses.

The results of the trials have shown that the combination of these drugs increased the risk of serotonergic side effects.

When using the fixed doses – Phentermine 15mg and Lorcaserin 10mg, the most common side effects were:

  • headache,
  • fatigue,
  • constipation,
  • dry mouth,
  • dizziness.

Coadministration of the two anorectics did not increase the weight loss rate.

Therefore, the scientists concluded that their combined use does not provide extra benefit and concomitant use of these drugs is inappropriate.

It is not recommended to combine Lorcaserin with Phentermine and any other prescription or over-the-counter slimming drugs.

Where Lorcaserin does not provide a significant weight loss, stop taking it before you begin using any other weight loss drug.

What is the difference between Lorcaserin and Phentermine?

The key difference between these two drugs is their different mechanisms of action.

Phentermine affects mostly the noradrenergic and dopaminergic receptors of the central nervous system (CNS), while Lorcaserin stimulates the serotonergic receptors of the CNS.

Despite the fact that Lorcaserin and Phentermine affect different types of the CNS receptors, both these drugs provide anorexigenic effect and help controlling the appetite.

Besides the different mechanism of action, these two anorectics have different side effects and dose regimen.

The most common side effects of Phentermine are:

  • insomnia,
  • headache,
  • dry mouth,
  • rapid heartbeat,
  • skin rash,
  • constipation.

The most common side effects of Lorcaserin are:

  • dry mouth,
  • headache,
  • fatigue,
  • dizziness,
  • constipation,
  • nausea.

These drugs have different contraindications for use.

Therefore, if Phentermine causes severe side effects, it can be replaced with Lorcaserin, and vice-versa.

Lorcaserin in Egypt

Belviq generic drugs (Lorcaserin 10mg pills) are supplied to Egypt by five companies.

You can buy Belviq generic drugs under the original names, such as:

  • LorcaSlim,
  • Lorcaviq,
  • PerfectSlim,
  • Tughtviq,
  • nonproprietary name Lorcaserin.

The price of Lorcaserin generic drugs is several times lower than the price of Belviq pills (by Eisai).

Unlike Eisai, the manufacturers of Belviq generic drugs have not used the potential of their scientific research centers and have not invested dozens of millions of dollars in development of Lorcaserin molecular formula.

Where to buy Lorcaserin?

As mentioned, Arena Pharmaceuticals has planned to get license to sell Lorcaserin in the EU and the UK in 2013.

In May 2013, the company withdrew its application for license to sell Lorcaserin pills in European countries.

Information about when Arena Pharmaceuticals will try to get license to sell Lorcaserin in the UK and the EU again is not available yet.

  • In 2018, the EU and the UK inhabitants can buy Lorcaserin only on online pharmacies.

If you have decided to buy Lorcaserin online, but have never ordered a delivery of anti-obesity medications on online pharmacies, consult your doctor before placing your order.

When buying Lorcaserin online, you should keep in mind that the sale or purchase of Lorcaserin without a prescription is illegal and prohibited.

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