Slim Fizz

Slim Fizz is effervescent tablets for weight loss that have become popular in the UK since July 2015. The first reviews about Slim Fizz were published in the British tabloid Daily Mail. Due to the publication of Slim Fizz review in the very popular tabloid, thousands of obese men and women learned about new Slim Fizz diet pills in just a few days.

The readers of Daily Mail online-version have left more than 150 comments to Slim Fizz review and actively distributed information about these diet pills in the popular social networks (Facebook and Twitter as well).

Agiotage around the new weight loss product – Slim Fizz was caused by the fact that the author of the review claims that Slim Fizz provides incredibly rapid weight loss. In the Slim Fizz review published in Daily Mail, one can familiarize with a “success story”, as well as pictures of women “before” and “after” Slim Fizz use.

The author of the review claims that Slim Fizz tablets helped to reduce weight by 5lb in just 10 days. Pictures “before” and “after” using Slim Fizz (after weight loss program) demonstrate that the author of the Slim Fizz review really managed to lose weight significantly.

The manufacturer of Slim Fizz claims that this weight loss product helps to “lose” up to 15lb in just 3 months. Unfortunately, the manufacturer of Slim Fizz cannot guarantee that body weight will not increase again after the end of weight loss program.

How does Slim Fizz work?

slim-fizzSlim Fizz effervescent tablets include active substance Glucomannan (alternative name: konjac mannan). Glucomannan is a natural soluble fibre, which well absorbs moisture.

Under the influence of moisture, the amount of glucomannan fibers increases and they are transformed into high-viscosity jelly-like mass. Glucomannan is gradually transformed into jelly within a few minutes after contact with water.

Due to the ability of glucomannan to swell, to increase in volume and to expand in the stomach, it stimulates the feeling of satiety after the oral use.

The uniqueness of Slim Fizz tablets is in that they should be dissolved in water before using. The use of dissolved Slim Fizz tablets eliminates the probability that glucomannan dietary fibers will swell in the esophagus and cause suffocation.

Unlike other glucomannan-containing weight loss products, Slim Fizz works directly in the stomach and does not create potential risks to normal breathing.

The manufacturer of Slim Fizz states that this slimming product does not cause side effects. However, comments about the fact that discomfort in the stomach can occur after Slim Fizz use, can be found in the customers’ reviews.

The new Slim Fizz weight loss tablets are manufactured by the British company, On-Group Ltd. The key brand of this company is proto-col. Under the brand proto-col, different weight loss products such as Slim Fizz, Thermo-Lite, Carb-Lite, L-carnitine, Pure Arginine are promoted.

For several weeks, Slim Fizz effervescent slimming tablets were sold on Amazon. Potential buyers of weight loss products had the possibility to buy Slim Fizz online in the UK, U.S., Canada and other worldwide countries.

Obese Britons had the opportunity to choose “next day delivery” of Slim Fizz. However, less than a month after the start of retail sales, the access to Slim Fizz purchase on Amazon was limited.

The manufacturer of Slim Fizz asserts that due to high demand, the entire stock of Slim Fizz was quickly sold out. Herewith, On-Group Ltd continues to take orders for Slim Fizz tablets, but does not clarify delivery terms of this weight loss product.

It should be noted that Slim Fizz is not the only over the counter slimming product containing soluble dietary fibres – glucomannan.

At Canadian pharmacies, glucomannan-containing weight loss products are sold under the brands Fibre & Weight Balance, Slimit, Beslim Slimphin and many others. In the country you live, glucomannan tablets and capsules can be sold under other trade names.

If you decide to buy glucomannan or other weight loss product online, read the terms of payment and delivery before making the order.

Phentermine influence on making decisions

In 2015, a resident of Florida (the USA) purchased a two-storey house at auction and paid for it a little more than $100,000. The initial price of this house at auction was $290,000.

Within a few days, this woman was sure that she bought two-storey house at very low price. However, in just a few days after the buying of house, she was shocked by the news that in addition to $ 100,000, she needs to pay Chase Mortgage charge of $400,000. careful study of conditions of house purchase, the woman tried to cancel the deal in court. The main motive for the deal termination was the fact that the woman began taking Phentermine pills shortly before the house purchase.

The woman claims that Phentermine pills negatively affect her ability to make informed decisions. However, the organizers of the auction claim that the house was sold properly, so there are no objective reasons for the deal cancellation.

Phentermine really can cause psychiatric side effects. However, it is almost impossible to prove that the therapeutic doses of Phentermine forced the woman to make uninformed decisions.

The list of Phentermine side effects includes several severe CNS side effects, such as clumsiness, confusion, dizziness, dysphoria, euphoria, headache, insomnia, overstimulation, psychosis, restlessness, tiredness, and tremor.

Unfortunately, the woman purchased the house has no convincing evidence that the decision was made under the Phentermine influence. Therefore, the chances to cancel the deal of buying a home are equal to zero.

In the USA, Phentermine is taken by hundreds of thousands of obese men and women. Therefore, the story of buying a home in the USA is not the only curious case related to the use of Phentermine anorectic.

Other unsuccessful examples, as well as success stories associated with Phentermine use can be found in the previous and the next reviews.

Saxenda cost

The cost of innovative weight loss drug – Saxenda is very high. Therefore, the developer and manufacturer of Saxenda (Novo Nordisk) should not expect a rapid growth of its sales.

In the USA, Saxenda cost is several times higher than that of other innovative drugs and several dozen times higher than that of slimming drugs available for sale for several decades.

Right now, you can:

• Compare Saxenda cost with the prices of new FDA-approved slimming drugs – Belviq and Qsymia.
• Compare Saxenda cost with the prices of the most prescribed FDA-approved drugs – Adipex, Suprenza, Bontril, Didrex, Xenical and Alli.

By choosing Saxenda new drug for weight loss, be ready to the fact that the cost of one day of anti-obesity therapy is about $35.5 US. Thus, in just a year of anti-obesity therapy, it is required to spend about $13.000 US for buying Saxenda.

Other new anti-obesity drugs – Belviq and Qsymia are more than 5 times cheaper than Saxenda. Within a year of weight loss therapy, it is required to spend no more than $2.400 US on buying Belviq, and from $2.000 US and more – on buying Qsymia pills.

saxedra_rxDespite the fact that Qsymia and Belviq are significantly cheaper than Saxenda, they are also unaffordable for obese people with middle and low income. The key cause of high price of new anti-obesity drugs is in the absence of Qsymia, Belviq and Saxenda generic drugs.

The manufacturers of Belviq, Saxenda and Qsymia do not have to compete with the manufacturers of bioequivalent drugs. Thus, the price of these drugs will remain high until the term of their patent protection expires and cheaper generic versions of Qsymia, Saxenda and Belviq appear at the US market.

It should be noted that in the USA some drugs are sold for over 15 years, but are still very expensive. For example, Americans who choose Xenical 120mg pills for weight loss are forced to spend on their buying more than $450 US every month (more than $5.400 US per year).

Only a small percent of obese people can annually spend on diet pills 2, 5, 10 or 15 thousand US dollars. Therefore, the vast majority of obese Americans will always use cheap diet pills that are ten times cheaper than prescription weight loss drugs – Belviq, Saxenda, Xenical or Qsymia.

The cheapest prescription diet pills available at the US market are included in the pharmacological group of sympathomimetic amines. Potential consumers of cheap diet pills may know sympathomimetic amines under the nonproprietary names:

• Phentermine
• Benzphetamine
• Diethylpropion
• Phendimetrazine

… or original brand names:

• Didrex (for Benzphetamine)
• Tenuate (for Diethylpropion)
• Bontril (for Phendimetrazine)
• Adipex, Suprenza (for Phentermine)

All the drugs mentioned above help to reduce weight by suppressing appetite. These drugs have almost the identical indications and contraindications, but the prices are different.

Diet pills sold under the nonproprietary names are cheaper than bioequivalent diet pills registered under the original brand. Furthermore, the drug price may depend on the dosage form.

For instance:

• When choosing usual Phentermine oral tablets or capsules, the minimum cost of anti-obesity therapy is about $20 US per month.
• When choosing Adipex (Phentermine) oral capsules or tablets, the minimum cost of the obesity treatment is a little more than $60 US per month.
• When choosing Suprenza (Phentermine) orally disintegrating tablets, the cost of weight loss therapy is about $110 US monthly.

Phentermine-containing drugs can be used only for a short-term therapy of obesity up to 3 months. Therefore, it is inappropriate to calculate the cost of one year of the obesity treatment using Phentermine.

If to compare the price of a Phentermine dose and a Saxenda dose, Saxenda drug is 53 times more expensive than Phentermine. Herewith, one day of obesity treatment with Saxenda is almost 2 times more expensive than one month of the obesity treatment with Phentermine.

It should be noted that there are cheaper diet pills than Phentermine at the US market. For example, in regular use of the minimal daily dose of Phendimetrazine 35mg, the costs of a month of obesity treatment are less than $110 US.

Information on the cost of Saxenda and other FDA-approved weight loss products listed in this review is relevant for the end of 2014 – beginning of 2015. Taking into account inflation and changing competitive environment, the prices of weight loss drugs mentioned in this review may differ from the current prices.

Saxenda contraindications

The list of Saxenda contraindications includes just a few diseases and conditions. Saxenda slimming drug should not be prescribed to overweight and obese men and women with:

• multiple endocrine neoplasia type 2 (MEN 2)
• medullary thyroid cancer (MTC) or family history of MTC
• allergy to anorexigenic agent – Liraglutide or inactive ingredients of Saxenda.

Children, adolescents under 18 years and pregnant women did not participate in clinical trials of Saxenda. Therefore, these groups of patients should be prescribed with alternative drugs for the obesity treatment instead of Saxenda.

Besides the list of contraindications, Product Monograph (Highlights of Prescribing Information) for Saxenda includes the list of cautions.

Saxenda cautions

Saxenda injections should not be prescribed to patients, who are taking or planning to take other drugs included in the pharmacological group of glucagon-like peptide-1 (GLP-1) receptor agonists, such as:

• Albiglutide (Eperzan)
• Dulaglutide (Trulicity)
• Lixisenatide (Lyxumia)
• Exenatide (Bydureon, Byetta)

Moreover, Saxenda should not be used in the combination with insulin and other prescription or over-the-counter weight loss products.

saxendaIf inflammation of pancreas occurred and pancreatitis was diagnosed during medical therapy of obesity, Saxenda use should be stopped. The main symptom of pancreatitis is severe abdominal pain.

Saxenda can cause a significant reduction of blood sugar level. Therefore, after the monitoring of blood glucose parameters, diabetic patients taking Saxenda may require the adjustment of daily doses of hypoglycemic drugs.

Some patients using Saxenda may develop gallstone disease. Data of clinical studies is insufficient to claim that gallstone disease is caused by Saxenda.

Nevertheless, if problems with gall bladder or bile ducts occur, it is necessary to stop using Saxenda and diagnose the cause of gallstone disease symptoms.

During clinical studies, it was recorded individual cases of thyroid cancer. However, a causal relationship between Saxenda use and thyroid cancer was not established. Nevertheless, the signs of thyroid cancer require an immediate cancellation of Saxenda. The main signs of thyroid cancer are increase in the size and mass of the neck, hoarseness, reduction in the frequency and depth of breathing, inflammation of the esophagus.

Saxenda may cause a slight increase in heart rate. Thus, obese patients with tachycardia require a regular monitoring of heart rate after the start of Saxenda use.

Saxenda can affect kidney functions. Therefore, patients with renal insufficiency should take Saxenda with caution.

In 0.2 % obese patients, treated with Saxenda during clinical studies, had suicidal thoughts and signs of depression. If unusual behavior or signs of anxiety disorder are observed after the start of Saxenda use, be sure to inform your treating physician.

Phentermine by Dream Pharma

Dream Pharma is one of the largest South Korean suppliers of anorexigenic drug – Phentermine.

• Since 2003, Dream Pharma owns a marketing authorization for Phentermine 37.5mg tablets (white, guitar-shaped tablets).

• In 2007, Dream Pharma announced the launch of sales of Phentermine 30mg capsules (blue and white capsules).

• Since 2014, Dream Pharma has started to supply in South Korea Phentermine 18.75mg tablets (pink, bean-shaped tablets).

Dream Pharma is one of the few suppliers of Phentermine tablets and capsules, which registered their trade names in two languages – Korean and English.

05English-speaking consumers of prescription weight loss products know Phentermine pills by Dream Pharma under the brand names Panbesy SR and Furimin.

It should be noted that a few decades ago, Panbesy brand was very popular in Belgium and Luxembourg.

However, after the European Medicines Agency withdrew a centralized license for Phentermine-containing drugs, the sale of Panbesy capsules was discontinued in Europe.

In 2015, Panbesy (Phentermine) drug is sold in several countries of the world, such as South Korea (Dream Pharma*), Hong Kong (LF Asia*) and Singapore (Euro Asia Medico*).

*The owner of marketing authorization

Besides Phentermine tablets and capsules, Dream Pharma supplies another two weight loss drugs in South Korea:

1. Phendimetrazine Tartrate
2. Diethylpropion Hydrochloride

Just as Phentermine, Phendimetrazine and Diethylpropion drugs have anorexigenic effect, therefore after their use an obese person can significantly limit the consumption of high-calorie food.

Phendimetrazine and Diethylpropion are the FDA-approved drugs sold in the USA for several decades.

Americans better know Phendimetrazine weight loss tablets under the brand name Bontril, but Diethylpropion tablets are sold under the brand names Tenuate and Tenuate Dospan at the US pharmacies.

Information about other manufacturers and suppliers of Diethylpropion, Phentermine and Phendimetrazine you can find out in our reviews.

Movement without pain

Regular physical loads are as important for weight loss as healthy diet and maintenance of normal metabolism. However, people predisposed to obesity face serious problem, which significantly restricts their physical activity.

This problem is that joints experience excessive load because of extra pounds. Herewith, intensive physical loads aggravate joint problems.

foot+painIf there is no discomfort in the joints before workouts in the gym, regular jogging or biking; after the start of workouts – nagging pain can force you to reduce the intensity of physical exercises or to refuse from them at all.

The lack of physical activity significantly reduces the efficiency of fighting excess weight. Therefore, trying to lose weight, do not forget that joints require additional protection when increasing physical loads.

Without reliable protection of joints, aching joint pain, which previously occurred only when walking or performing exercise, will occur at rest.

In this case, any physical loads should be stopped, but to restore the function of joint tissue – a long time is required.

So that the joints maintain their mobility, as well as are not destroyed by intensive exercise, joint and connective tissue should be nourished with the glucosamine and chondroitin.

Glucosamine and chondroitin are building components of cartilage tissue that inhibit the development of degenerative processes in the joints and restore their function.

Therefore planning physical activities that stimulate rapid fat burning, be sure not to forget about the health of joints. After all, weight loss should be not only rapid, but also safe.

Otherwise, after solving the problem of excess weight, solution of the problem with aching and inflamed joints will be required.

Is Meridia better than Phentermine?

Meridia diet pills came into the market at the end of 90s of last century. More than 15 years ago, many experts believed that Meridia is much safer than Phentermine-containing drugs and Phentermine era comes to the end.

For hundreds of thousands of patients, Meridia drug was really better than Phentermine. However, statements that Meridia is safer than Phentermine proved premature.

meridiaThirteen years after the start of Meridia retail sales, researchers paid attention to the fact that long-term cardiovascular side effects develop in obese people using Meridia.

Compared to Phentermine side effects, cardiovascular side effects of Meridia posed a more serious danger to human health. Therefore, despite the fact that serious cardiovascular pathologies were diagnosed only in a few people used Meridia, this drug was recognized unsafe and its sale was terminated.

During the whole period of retail sales of Meridia, this drug was better choice for obese people who had contraindications to Phentermine and other amphetamine-like appetite suppressants.

After Meridia withdrawal from the US market, only amphetamine-like weight loss products for appetite control were sold at the U.S. pharmacies. Therefore, after the cessation of Meridia sales, access to medical appetite suppressant therapy was limited to tens of thousands of obese Americans.

Between 2010 and 2012, only amphetamines were used to control appetite in the USA. In June 2012, the FDA approved a new weight loss drug – Lorcaserin, which is not an amphetamine-like.

Thus, obese Americans who had contraindications to Phentermine again have the opportunity to conduct an intensive obesity therapy not only by means of a healthy diet and physical exercises, but also by means of appetite suppressant.

Just as 15 years ago, today the opinion is expressed that Lorcaserin is better than Phentermine and less often causes side effects. However, Phentermine always has a distinct advantage is that it is used for the obesity treatment for more than 50 years.

Therefore, all potential risks of Phentermine are well studied, the body’s reaction to the change of Phentermine dose is predictable, but the health benefits of an obese person is undeniable.

Diet pills by Korea Prime Pharm

Korea Prime Pharm is the South Korean supplier of prescription diet pills – Phentermine and Phendimetrazine. Both these drugs are approved as obesity treatment in patients with BMI of 27 and higher.

Phentermine and Phendimetrazine by Korea Prime Pharm are registered in South Korea under the original brands in Korean language. At the international pharmaceutical market, Korea Prime Pharm has registered these brand names in English:

  • Pender – for Phentermine 37.5mg tabs
  • Pendimen – for Phendimetrazine 35mg tabs

Pendimen (Phendimetrazine) diet pills

White, guitar-like Pender (Phentermine) tabs and white, round Pendimen (Phendimetrazine) tabs were approved to treat obesity in December 2009. Today, Korea Prime Pharm does not supply Phentermine and Phendimetrazine in English-speaking countries.

Thus, Pender and Pendimen brands are not known to potential buyers of anorectic drugs in the USA, Australia, Canada, the UK, Ireland, and New Zealand.

Inhabitants of English-speaking countries better know Phentermine-containing drugs under the brands Duromine, Ionamin and Adipex, but Phendimetrazine-containing drugs under the brand Bontril.

If you want to buy Phentermine or Phendimetrazine anorectic but Pender, Bontril, Adipex, Pendimen or Duromine diet pills are not sold in your country, it is quite possible that the sale of diet pills containing amphetamine-like drugs – Phendimetrazine or Phentermine is prohibited.

Obesity risk factors

Modern society created a stereotype on that a sedentary life is the key problem of obesity. However, many experts draw our attention to the fact that the obesity rate has sharply increased over the last 30 years. Still, the levels of physical activity almost have not changed.

Thus, the statement that the waist size increases due to low physical activity is unreliable. The thing is that a well-balanced diet helps to keep a beautiful body shape even if a person does not do fitness or sports.

Well, malnutrition and insufficient physical activity are not the only reasons why people become obese; there is one more – stress.

Over the decades, American researchers had been watching over teenagers and concluded that children prone to stress had higher risk of obesity than children who were raised in harmony and a healthy emotional atmosphere.

The researchers name several stressful situations that may cause obesity in teenagers.

• The psychological risk factors of weight gain in girls may be a stress caused by unstable financial situation in the family or parents’ divorce.

• It is believed that stress caused by serious problem of mother’s health one of the psychogenic risk factors of obesity in boys.

Despite the fact that the causes of obesity in children and adults may differ, the method of anti-obesity treatment slightly depends on a person’s age.

1. The first step towards weight loss in children and adults – is a gradual increase of physical activity.
2. The second step to weight loss – is a gradual elimination of fast food and high-calorie fatty food from daily diet.

If the body weight is reduced by less than 5% of the initial weight in three months after the anti-obesity treatment, people can make the third step towards a significant weight loss.

To lose weight rapidly, people can use diet pills, medical devices or surgery. But in most cases, people use diet pills to cure obesity at home.

Obesity risk factorsTo buy the most effective diet pills – you need a prescription. It has to be noted that highly effective anti-obesity drugs are only prescribed to those people, who has the appropriate indications for use of these drugs.

In the USA, Phentermine pills were the best diet pills over the last 50 years. These diet pills have been successfully used for weight loss for many decades. Therefore, their effectiveness was confirmed during the numerous clinical studies and thousands real reviews on Phentermine ability to stimulate the quick weight loss.

You can find both positive and negative feedbacks about Phentermine on the Internet forums. The main drawback of Phentermine pills is that their efficiency starts to decrease over a couple of months after the beginning of the treatment. Therefore, those people who did not manage to lose weight by means of Phentermine within 2-3 months, have to search some new methods to fight obesity.

If Phentermine pills are ineffective, you can always replace them by other diet pills that are available over-the-counter or by prescription only at pharmacies. Please note that over-the-counter weight loss supplements are less effective than Phentermine.

However, unlike Phentermine that can cause drug dependence and severe cardiovascular side effects, over-the-counter weight loss products are completely safe for human health.

In 2015, Phentermine pills are used for the treatment of obesity only in a few countries of the world. The highest volume of retail sales of Phentermine was registered in the USA. In addition, Phentermine pills are the leaders on the Australian market of weight loss products.

Some international distributors of weight loss products offer to buy Phentermine online in any country of the globe. When buying Phentermine online, a purchaser must know that the wholesale and retail sales of Phentermine without prescription – are illegal.

Herewith, only those Companies can import Phentermine to the USA or Australia, which own the marketing authorization for Phentermine in these countries.

Duromine effects

Besides that Duromine diet pills suppress appetite, they can influence physiological systems, internal organs and mental health of the person. Reduced appetite, increase in thermogenesis and metabolism are therapeutic effects of Duromine that help significantly to lose weight in just a few weeks.

Apart from therapeutic effects, Duromine can cause side effects including undesired impact on the functions of cardiovascular system.

• If side effects of Duromine do not create a serious threat to health, anti-obesity therapy can be conducted without any restrictions.

• If Duromine causes severe side effects, special precautions can be required during the obesity treatment.

Duromine effects: fertility

PregnancyDuromine pills have been studied for weight loss for over 20 years and their impact on fertility is well studied. The results of studies demonstrate that Duromine does not affect the female reproductive function. Therefore, the chances to become pregnant prior anti-obesity therapy are the same as after the end of using Duromine pills.

Duromine does not affect the sperm morphology and male reproductive function, but can cause erectile dysfunction. Despite the fact that Duromine pills do not affect the male fertility, some men lose the ability to conceive after the start of using them.

If a woman gets pregnant during the drug therapy of obesity, she should stop using Duromine pills and inform the doctor about the pregnancy. To evaluate the Duromine effect on the fetus, the doctor will prescribe the woman a series of diagnostic tests. Only after the results of these tests, the doctor can recommend to keep or terminate the pregnancy.

To terminate pregnancy in the first days after sexual act, emergency hormonal contraception can be used. If a woman taking Duromine finds out she is pregnant a few weeks after sexual act, she should discuss with her treating doctor the optimal method of contraception.

To prevent unwanted pregnancy during the drug therapy of obesity, men and women taking Duromine should use reliable contraception methods.

Duromine effects: teeth

Duromine does not destroy tooth enamel and does not cause tooth decay, but causes dryness in the mouth. Because of saliva deficiency in the oral cavity, dental plaque is very quickly formed on the teeth because of which the diseases of teeth and gums can develop.

In order to prevent undesirable Duromine effects on the teeth health, chewing gum, regular tooth brushing and mouthwashes can be used to stimulate salivation.