Slim Fizz

Slim Fizz is effervescent tablets for weight loss that have become popular in the UK since July 2015. The first reviews about Slim Fizz were published in the British tabloid Daily Mail. Due to the publication of Slim Fizz review in the very popular tabloid, thousands of obese men and women learned about new Slim Fizz diet pills in just a few days.

The readers of Daily Mail online-version have left more than 150 comments to Slim Fizz review and actively distributed information about these diet pills in the popular social networks (Facebook and Twitter as well).

Agiotage around the new weight loss product – Slim Fizz was caused by the fact that the author of the review claims that Slim Fizz provides incredibly rapid weight loss. In the Slim Fizz review published in Daily Mail, one can familiarize with a “success story”, as well as pictures of women “before” and “after” Slim Fizz use.

The author of the review claims that Slim Fizz tablets helped to reduce weight by 5lb in just 10 days. Pictures “before” and “after” using Slim Fizz (after weight loss program) demonstrate that the author of the Slim Fizz review really managed to lose weight significantly.

The manufacturer of Slim Fizz claims that this weight loss product helps to “lose” up to 15lb in just 3 months. Unfortunately, the manufacturer of Slim Fizz cannot guarantee that body weight will not increase again after the end of weight loss program.

How does Slim Fizz work?

slim-fizzSlim Fizz effervescent tablets include active substance Glucomannan (alternative name: konjac mannan). Glucomannan is a natural soluble fibre, which well absorbs moisture.

Under the influence of moisture, the amount of glucomannan fibers increases and they are transformed into high-viscosity jelly-like mass. Glucomannan is gradually transformed into jelly within a few minutes after contact with water.

Due to the ability of glucomannan to swell, to increase in volume and to expand in the stomach, it stimulates the feeling of satiety after the oral use.

The uniqueness of Slim Fizz tablets is in that they should be dissolved in water before using. The use of dissolved Slim Fizz tablets eliminates the probability that glucomannan dietary fibers will swell in the esophagus and cause suffocation.

Unlike other glucomannan-containing weight loss products, Slim Fizz works directly in the stomach and does not create potential risks to normal breathing.

The manufacturer of Slim Fizz states that this slimming product does not cause side effects. However, comments about the fact that discomfort in the stomach can occur after Slim Fizz use, can be found in the customers’ reviews.

The new Slim Fizz weight loss tablets are manufactured by the British company, On-Group Ltd. The key brand of this company is proto-col. Under the brand proto-col, different weight loss products such as Slim Fizz, Thermo-Lite, Carb-Lite, L-carnitine, Pure Arginine are promoted.

For several weeks, Slim Fizz effervescent slimming tablets were sold on Amazon. Potential buyers of weight loss products had the possibility to buy Slim Fizz online in the UK, U.S., Canada and other worldwide countries.

Obese Britons had the opportunity to choose “next day delivery” of Slim Fizz. However, less than a month after the start of retail sales, the access to Slim Fizz purchase on Amazon was limited.

The manufacturer of Slim Fizz asserts that due to high demand, the entire stock of Slim Fizz was quickly sold out. Herewith, On-Group Ltd continues to take orders for Slim Fizz tablets, but does not clarify delivery terms of this weight loss product.

It should be noted that Slim Fizz is not the only over the counter slimming product containing soluble dietary fibres – glucomannan.

At Canadian pharmacies, glucomannan-containing weight loss products are sold under the brands Fibre & Weight Balance, Slimit, Beslim Slimphin and many others. In the country you live, glucomannan tablets and capsules can be sold under other trade names.

If you decide to buy glucomannan or other weight loss product online, read the terms of payment and delivery before making the order.

Regimex Review

Regimex is an anorectic drug approved by the FDA as an obesity treatment in September 2010. In 2015, plastic bottles containing 100 round, pink Regimex diet pills are supplied at the US market.

Each Regimex diet pill contains 25mg or 50mg of anorectic agent – Benzphetamine (as Hydrochloride). The same doses of Benzphetamine are contained in Didrex diet pills that were sold in the USA for several decades.

Regimex is a generic version of Didrex. Correspondingly, just as Didrex, Regimex is sold at the US pharmacies by prescription.

• The manufacturer of Regimex medication is WraSer Pharmaceuticals.
• The owner of marketing authorization for Regimex in the USA is Mikart Pharma.

In late 2012, WraSer Pharma planned to launch retail sale of Regimex in the USA. However, American consumers of weight loss products had the opportunity to buy Regimex only in early 2013.

Regimex is used for weight loss in patients with BMI of 30 and higher. Regimex side effects are the same as that of other amphetamine-like anorectics, including Adipex (Phentermine).

There are no significant differences between Regimex (Benzphetamine) and Adipex (Phentermine). Both these weight loss drugs reduce hunger and help to control appetite.

REGIMEXThe only significant difference between Regimex and Adipex is the price. Adipex is one of the most expensive diet pills available at the US market. Thus, when choosing diet pills, obese Americans compare the price of Adipex and Regimex and then pay attention to the effectiveness and safety of these anorectics.

 
Before comparing Regimex price with the price of other anorectic medications, discuss with your doctor the optimal dose of Regimex and dose of other anorectics.

For example, the doctor may recommend taking Regimex 25mg pills three times per day or instead of Regimex may prescribe Adipex 37.5mg pills that are taken just once daily.

In this case, when comparing the price of anorectics, it is necessary to compare the price of an Adipex 37.5mg pill with the price of three Regimex 25mg pills.

Many US pharmacies provide the opportunity to buy Regimex (Benzphetamine) at a discount. To buy Regimex at discount price, it is necessary to get a coupon from the attending physician or print the coupon for Regimex on the Internet.

The manufacturer of Regimex claims that when buying these diet pills at a discount, the price of a Regimex 25mg package is no more than $15 US. If you want to buy Regimex without a prescription, you can find Benzphetamine-containing drugs on online pharmacies. Just as the US retailers, online pharmacies offer to buy Regimex at a discount (with or without the coupon).

Razin Review

Razin_arizaRazin is a trade name of diet pills available on Israeli market of weight loss products. The original name of Razin pills in Hebrew – רזין. In the production of Razin diet drug, Phentermine anorexigenic agent is used.

At Israeli pharmacies, people can buy Razin diet pills containing 15mg of active ingredient – Phentermine (in form of resinat). Other dosage strengths of Razin (Phentermine) are not produced and not sold.

Razin diet pills were included to Israel Drug Registry in June 1992. In August 2012, the marketing authorization for Razin (Phentermine) was extended until August 2022.

CTS Chemical Industries (part of CTS Group) is the manufacturers and distributor of Razin (Phentermine). This pharmaceutical company is the only Israeli supplier of Phentermine-containing pills in 2015.

• CTS supplies packages containing 30 diet pills of Razin 15mg (3 blisters x 10 Razin pills) to Israeli market.
• The color of original Razin (Phentermine) pills – orange-purple. The expiration date of Razin 15mg pills – 3 years.

In 2012, CTS published a leaflet for Razin (PDF), which said that these Phentermine-containing pills could be prescribed to adolescents over 12 years old for anti-obesity treatment.

In Israel, Razin (Phentermine) pills are approved for anti-obesity mono-therapy in patients over 16 years old. Therefore, we may assume that Razin (Phentermine) leaflet, published by CTS, has been focused on Israeli exporters of Phentermine.

In some other countries, Phentermine is actually used for a teenage obesity treatment in children over 12 years old. For instance, in the UK – Phentermine pills for teenage obesity treatment are sold under the brand name Ionamin, while in Australia – under the brand name Duromine.

Another distinctive feature of Razin (Phentermine) pills is that they were approved in Israel for the treatment of morbid obesity in patients with BMI 30 and higher.

Australia is one of a few countries, where Phentermine can be prescribed for overweight men and women with BMI over 25. In the UK, USA and many other countries, Phentermine pills can be prescribed for weight loss in pre-obese patients, whose BMI is 27 and higher.

In Israel, as well as in other countries, Phentermine (Razin) is approved for a short-term weight loss therapy, lasting for 12 weeks. The recommended dose of Razin – one diet pill per day.

One diet pill of Razin 15mg equals to one diet pill of Duromine 15mg (or Ionamin 15mg). If you want to buy Phentermine 15mg pills, but you do not know under what brands they are available in your town, then you can find information on different Phentermine-containing drugs in our reviews.

For more information on Razin, visit your physician, pharmacist, or check out other blogs dedicated to Phentermine-based diet drugs and online forums, where people discuss the obesity problem.

Phentermine influence on making decisions

In 2015, a resident of Florida (the USA) purchased a two-storey house at auction and paid for it a little more than $100,000. The initial price of this house at auction was $290,000.

Within a few days, this woman was sure that she bought two-storey house at very low price. However, in just a few days after the buying of house, she was shocked by the news that in addition to $ 100,000, she needs to pay Chase Mortgage charge of $400,000.

woman.mortgage.house_After careful study of conditions of house purchase, the woman tried to cancel the deal in court. The main motive for the deal termination was the fact that the woman began taking Phentermine pills shortly before the house purchase.

The woman claims that Phentermine pills negatively affect her ability to make informed decisions. However, the organizers of the auction claim that the house was sold properly, so there are no objective reasons for the deal cancellation.

Phentermine really can cause psychiatric side effects. However, it is almost impossible to prove that the therapeutic doses of Phentermine forced the woman to make uninformed decisions.

The list of Phentermine side effects includes several severe CNS side effects, such as clumsiness, confusion, dizziness, dysphoria, euphoria, headache, insomnia, overstimulation, psychosis, restlessness, tiredness, and tremor.

Unfortunately, the woman purchased the house has no convincing evidence that the decision was made under the Phentermine influence. Therefore, the chances to cancel the deal of buying a home are equal to zero.

In the USA, Phentermine is taken by hundreds of thousands of obese men and women. Therefore, the story of buying a home in the USA is not the only curious case related to the use of Phentermine anorectic.

Other unsuccessful examples, as well as success stories associated with Phentermine use can be found in the previous and the next reviews.

Saxenda cost

The cost of innovative weight loss drug – Saxenda is very high. Therefore, the developer and manufacturer of Saxenda (Novo Nordisk) should not expect a rapid growth of its sales.

In the USA, Saxenda cost is several times higher than that of other innovative drugs and several dozen times higher than that of slimming drugs available for sale for several decades.

Right now, you can:

• Compare Saxenda cost with the prices of new FDA-approved slimming drugs – Belviq and Qsymia.
• Compare Saxenda cost with the prices of the most prescribed FDA-approved drugs – Adipex, Suprenza, Bontril, Didrex, Xenical and Alli.

By choosing Saxenda new drug for weight loss, be ready to the fact that the cost of one day of anti-obesity therapy is about $35.5 US. Thus, in just a year of anti-obesity therapy, it is required to spend about $13.000 US for buying Saxenda.

Other new anti-obesity drugs – Belviq and Qsymia are more than 5 times cheaper than Saxenda. Within a year of weight loss therapy, it is required to spend no more than $2.400 US on buying Belviq, and from $2.000 US and more – on buying Qsymia pills.

saxedra_rxDespite the fact that Qsymia and Belviq are significantly cheaper than Saxenda, they are also unaffordable for obese people with middle and low income. The key cause of high price of new anti-obesity drugs is in the absence of Qsymia, Belviq and Saxenda generic drugs.

The manufacturers of Belviq, Saxenda and Qsymia do not have to compete with the manufacturers of bioequivalent drugs. Thus, the price of these drugs will remain high until the term of their patent protection expires and cheaper generic versions of Qsymia, Saxenda and Belviq appear at the US market.

It should be noted that in the USA some drugs are sold for over 15 years, but are still very expensive. For example, Americans who choose Xenical 120mg pills for weight loss are forced to spend on their buying more than $450 US every month (more than $5.400 US per year).

Only a small percent of obese people can annually spend on diet pills 2, 5, 10 or 15 thousand US dollars. Therefore, the vast majority of obese Americans will always use cheap diet pills that are ten times cheaper than prescription weight loss drugs – Belviq, Saxenda, Xenical or Qsymia.

The cheapest prescription diet pills available at the US market are included in the pharmacological group of sympathomimetic amines. Potential consumers of cheap diet pills may know sympathomimetic amines under the nonproprietary names:

• Phentermine
• Benzphetamine
• Diethylpropion
• Phendimetrazine

… or original brand names:

• Didrex (for Benzphetamine)
• Tenuate (for Diethylpropion)
• Bontril (for Phendimetrazine)
• Adipex, Suprenza (for Phentermine)

All the drugs mentioned above help to reduce weight by suppressing appetite. These drugs have almost the identical indications and contraindications, but the prices are different.

Diet pills sold under the nonproprietary names are cheaper than bioequivalent diet pills registered under the original brand. Furthermore, the drug price may depend on the dosage form.

For instance:

• When choosing usual Phentermine oral tablets or capsules, the minimum cost of anti-obesity therapy is about $20 US per month.
• When choosing Adipex (Phentermine) oral capsules or tablets, the minimum cost of the obesity treatment is a little more than $60 US per month.
• When choosing Suprenza (Phentermine) orally disintegrating tablets, the cost of weight loss therapy is about $110 US monthly.

Phentermine-containing drugs can be used only for a short-term therapy of obesity up to 3 months. Therefore, it is inappropriate to calculate the cost of one year of the obesity treatment using Phentermine.

If to compare the price of a Phentermine dose and a Saxenda dose, Saxenda drug is 53 times more expensive than Phentermine. Herewith, one day of obesity treatment with Saxenda is almost 2 times more expensive than one month of the obesity treatment with Phentermine.

It should be noted that there are cheaper diet pills than Phentermine at the US market. For example, in regular use of the minimal daily dose of Phendimetrazine 35mg, the costs of a month of obesity treatment are less than $110 US.

Information on the cost of Saxenda and other FDA-approved weight loss products listed in this review is relevant for the end of 2014 – beginning of 2015. Taking into account inflation and changing competitive environment, the prices of weight loss drugs mentioned in this review may differ from the current prices.

Saxenda contraindications

The list of Saxenda contraindications includes just a few diseases and conditions. Saxenda slimming drug should not be prescribed to overweight and obese men and women with:

• multiple endocrine neoplasia type 2 (MEN 2)
• medullary thyroid cancer (MTC) or family history of MTC
• allergy to anorexigenic agent – Liraglutide or inactive ingredients of Saxenda.

Children, adolescents under 18 years and pregnant women did not participate in clinical trials of Saxenda. Therefore, these groups of patients should be prescribed with alternative drugs for the obesity treatment instead of Saxenda.

Besides the list of contraindications, Product Monograph (Highlights of Prescribing Information) for Saxenda includes the list of cautions.

Saxenda cautions

Saxenda injections should not be prescribed to patients, who are taking or planning to take other drugs included in the pharmacological group of glucagon-like peptide-1 (GLP-1) receptor agonists, such as:

• Albiglutide (Eperzan)
• Dulaglutide (Trulicity)
• Lixisenatide (Lyxumia)
• Exenatide (Bydureon, Byetta)

Moreover, Saxenda should not be used in the combination with insulin and other prescription or over-the-counter weight loss products.

saxendaIf inflammation of pancreas occurred and pancreatitis was diagnosed during medical therapy of obesity, Saxenda use should be stopped. The main symptom of pancreatitis is severe abdominal pain.

Saxenda can cause a significant reduction of blood sugar level. Therefore, after the monitoring of blood glucose parameters, diabetic patients taking Saxenda may require the adjustment of daily doses of hypoglycemic drugs.

Some patients using Saxenda may develop gallstone disease. Data of clinical studies is insufficient to claim that gallstone disease is caused by Saxenda.

Nevertheless, if problems with gall bladder or bile ducts occur, it is necessary to stop using Saxenda and diagnose the cause of gallstone disease symptoms.

During clinical studies, it was recorded individual cases of thyroid cancer. However, a causal relationship between Saxenda use and thyroid cancer was not established. Nevertheless, the signs of thyroid cancer require an immediate cancellation of Saxenda. The main signs of thyroid cancer are increase in the size and mass of the neck, hoarseness, reduction in the frequency and depth of breathing, inflammation of the esophagus.

Saxenda may cause a slight increase in heart rate. Thus, obese patients with tachycardia require a regular monitoring of heart rate after the start of Saxenda use.

Saxenda can affect kidney functions. Therefore, patients with renal insufficiency should take Saxenda with caution.

In 0.2 % obese patients, treated with Saxenda during clinical studies, had suicidal thoughts and signs of depression. If unusual behavior or signs of anxiety disorder are observed after the start of Saxenda use, be sure to inform your treating physician.

Duromine QA

• Can I use Duromine as a replacement by a healthy diet and regular exercise?

No, you cannot. Duromine should be used in the combination with drug-free methods to fight obesity, such as physical activity and a balanced diet.

• How do I learn whether I can use Duromine for the obesity treatment or not?

Duromine can be prescribed only by the doctors who have experience in treating patients with obesity or overweight. Duromine can be prescribed only to patients for whom benefits of using Duromine exceed the potential health risks.

• How to get a prescription for Duromine?

Before writing out a prescription for Duromine, the doctor should learn the current state of the patient and the history of all his diseases. For an objective assessment of mental and physical condition of the patient, a full medical examination may be required.

• Under what conditions can a doctor refuse to write out a prescription for Duromine?

The reason why a doctor may refuse to prescribe Duromine can be one or several risk factors, such as: uncontrolled hypertension, eating disorders (bulimia, anorexia), history of drug or alcohol abuse, pregnancy, planning a surgery requiring general anesthesia, the use of certain groups of drugs (antidepressants, antimigraine agents, MAO inhibitors), glaucoma, history of depression.

• How long should I use Duromine?

Duration of Duromine use depends on the rate of weight loss, presence / absence of side effects, the dynamics of change in the overall health. Regardless of obesity severity, the duration of Duromine use may vary from two weeks up to three months.

• What Duromine doses are used for the obesity treatment?

A Duromine 15mg capsule is the most prescribed daily dose for overweight patients with BMI of 25 to 29.9. The most prescribed dose of Duromine for obese patients with BMI of 30 and higher is 30mg. The maximum dose of Duromine 40mg is prescribed in rare cases.

• What side effects may occur after Duromine use?

Regardless of Duromine dose, a patient may experience dry mouth, dizziness, headache, gastric disorders, hypertension and other side effects. When the maximum dose of Duromine 40mg is used regularly, the risk of drug dependence increases.

• Does the weight increase after I stop taking Duromine?

After the end of medical therapy of obesity, body fat percentage can again start to increase. To prevent obesity, you should continue to adhere to a hypocaloric diet and to be physically active after the end of Duromine use.

• Can a doctor prescribe Duromine to children or adolescents?

In Australia, Duromine was approved as an obesity treatment in adolescents from 12 years and older. Children under 12 years did not participate in clinical trials of Duromine. It should be noted that in the USA, Phentermine-containing drugs (including Adipex) are not prescribed for the obesity treatment in adolescents under 16 years old.

• Where Duromine pills are manufactured?

Duromine 15mg, 30mg and 40mg pills are manufactured in Australia and imported to several countries, such as New Zealand, China (Hong Kong), Singapore, South African Republic. In Australia, Duromine pills were approved as an obesity treatment in 1991.

• What drugs can be used as an alternative to Duromine?

Dozens of drugs containing anorexigenic agent, Phentermine are available at the U.S. market of weight loss products. Most of these drugs are sold under the proprietary name Phentermine Hydrochloride.

In addition, Phentermine-containing diet pills are available at the U.S. pharmacies under the proprietary trademarks Suprenza and Adipex. Just as in Australia, in the USA Phentermine-containing diet pills are sold by prescription only.

Adipex 37.5mg FAQ

• What results can I achieve using Adipex 37.5mg?

For 3 months of using Adipex 37.5mg diet pills, people can lose up to 15% of their body weight. Patients can only achieve maximum weight loss, if they use Adipex 37.5mg weight loss tablets in combination with regular physical exercises and a low-calorie diet.

• Is there any risk of obesity relapse after termination of Adipex 37.5mg?

A gradual weight loss by means of Adipex 37.5mg provides a stable and long-term result. The weight regain after the termination of using Adipex 37.5mg capsules may occur only if a person returns to his previous lifestyle.

• How to avoid weight gain after I stop using Adipex 37.5mg?

A balanced diet and regular physical activity help to reduce the risk of weight regain. During the use of Adipex 37.5mg slimming pills, a person develops proper eating behavior. Healthy diet and active lifestyle after the withdrawal of Adipex 37.5mg capsules help to avoid body mass regain, as well as reduces weight.

• What long-term side effects may occur when using Adipex 37.5mg?

Long-term side effects are: headaches, depression and insomnia. If long-term side effects of Adipex 37.5mg are mild, they do not require any special treatment. If Adipex 37.5mg causes severe side effects, then a person can be prescribed a symptomatic treatment. Sometimes, when long-term severe side effects appear, doctors recommend to stop using Adipex 37.5mg diet capsules.

• Does Adipex 37.5mg have some negative effect on heart?

After the use of Adipex 37.5mg slimming capsules, the blood pressure and the heart rate may increase. Usually, these side effects are slightly pronounced, pass quickly and do not require a special treatment. To reduce the risk of side effects, do not combine Adipex 37.5mg pills with other CNS stimulants. If you have difficulty breathing and rapid heartbeat, after the use of Adipex 37.5mg diet pills, then you should stop using this anorexigenic drug.

• Can I take sleeping pills together with Adipex 37.5mg?

Please note that almost all sleeping pills remove the cause of sleep disorder by acting in the CNS. Adipex 37.5mg also stimulates the CNS. An excessive stimulation of the CNS may cause severe side effects. For treatment of sleep disorders, different groups of sleeping pills can be used. The interactions between Adipex 37.5mg and sleeping pills have not been studied well.

• Can Adipex 37.5mg increase the metabolic rate?

Regardless of obesity severity, Adipex 37.5mg can increase the resting metabolic rate.

• What happens in overdosage of Adipex 37.5mg?

The most common symptoms of overdosage of Adipex 37.5mg are: dizziness, tremor, difficult breathing, anxiety, nervousness, euphoria, tachycardia, seizures and coma. Overdosage of Adipex 37.5mg is accompanied by gastrointestinal disorders most of the times (nausea, diarrhea, vomiting or stomach cramps).

• Can I continue using Adipex 37.5mg pills in difficulty breathing?

Difficulty breathing when using Adipex 37.5mg capsules can be a symptom of some cardiovascular pathology (like pulmonary hypertension). Noticing this side effect, you should stop using Adipex 37.5mg.

• Can I take Adipex 37.5mg pills in early pregnancy?

Adipex 37.5mg (Phentermine) provides teratogenic effect and may cause potential threat for the fetus even at the stage of embryonic development. Therefore, Adipex 37.5mg weight loss drug is contraindicated during pregnancy.

• What birth control pills can be combined with Adipex 37.5mg?

Oral birth controls do not interact with Adipex 37.5mg, hence they can be used during the entire drug therapy. If plasma concentration of estrogen is very high, obese women are recommended to use birth control pills, containing progesterone only.

• Can I plan conception after Adipex 37.5mg withdrawal?

It is recommended to start planning conception only after a complete withdrawal of Adipex 37.5mg drug from the body (in 1-4 weeks after the use of the last Adipex 37.5mg dose).

• Is there any alternative to Adipex 37.5mg weight loss pills?

Some people have severe side effects after the use of Adipex 37.5mg weight loss capsules. In this case, Adipex 37.5mg capsules should be replaced by some other prescription anti-obesity drug (e.g. Sibutramine) or over-the-counter weight loss medication (e.g. Phen375).

Duromine safety

Many obese people have no contraindications to Duromine drug. However, there are also groups of people for whom the potential risks of Duromine exceed health benefits. Beginning to take Duromine, an obese person should remember that conditions for Duromine withdrawal could arise just a few days after the start of anti-obesity therapy.

Immediate cessation of Duromine use is required in the cases when this psychostimulant causes severe cardiovascular, gastrointestinal and psychiatric side effects.

• Symptoms of serious cardiovascular side effects of Duromine are chest pain, shortness of breath, palpitations.
• Potentially dangerous psychiatric side effects of Duromine are anxiety, insomnia, and psychosis.
• The most severe gastrointestinal side effects of Duromine can be abdominal pain and vomiting.

Severity of Duromine side effects depends on the taken dose. The higher the daily dose of Duromine, the higher the risk of severe side effects. In some cases, the severity of side effects depends on the frequency of Duromine use, rather than the size of the psychostimulant dose. Obese patients may be advised:

• Regular use of Duromine capsules (once a day, twice a day, once every 48 hours)
• Irregular use of Duromine capsules (for example, only when more than one gluttony attack occurs during the day)

weight-loss-motivationThose who have never taken psychostimulants suppressing appetite should start anti-obesity therapy with a minimal dose of Duromine 15mg. In the absence of pronounced side effects, Duromine dose can be increased up to 30 or 40 mg (in some countries Duromine 40mg capsules are not available). If side effects are mild after applying the maximum daily dose of Duromine, the course of obesity treatment can be continued.

The presence of obesity-related diseases can affect Duromine safety. For example, people prone to depression are at higher risk of psychiatric side effects than people without a history of mental illness.

Often, Duromine is absolutely safe and well tolerated only in the case if other prescription or over-the-counter drugs are not taken during the drug therapy of obesity.

 
Only doctor should assess the balance of efficiency and safety of Duromine. To properly evaluate the balance of benefits and risks of Duromine, both the study of the disease history and carrying out of diagnostic tests may be required.

Comprehensive medical examination is necessary in order to eliminate all possible risks associated with Duromine use and to make sure that there are no contraindications to this anorexigenic drug.

If you want to make sure that Duromine will help you to lose weight without causing potentially dangerous side effects, consult your doctor. Before to visit the doctor, you can get information about side effects and contraindications to Duromine use by email.

If you have one or several contraindications to Duromine use, you will not manage to get a prescription for this psychostimulant. In this case, you should discuss with your doctor the possibility of using safer anorexigenic drug to fight obesity.

Duromine efficiency

Before Duromine diet pills came into the market, they were well studied. In the development and clinical trials of Duromine pills, the employees of 3M Pharmaceuticals company (now 3M is a part of iNova) were participated.

After the successful completion of clinical trials, their results were sent to a study in the Ministries of Health of many countries. One of the first health authorities studied the results of Duromine clinical trials was Medsafe (New Zealand Medicines and Medical Devices Safety Authority).

By studying the trials results, Medsafe employees have concluded that the benefits of Duromine use exceed potential risks to the health of obese patients.

The results of clinical trials have demonstrated that it is possible to reduce body weight by 5-15% of initial one when using Duromine and observing all conditions of anti-obesity therapy.

It should be noted that efficiency of Duromine and efficiency of obesity therapy are different concepts.

Duromine efficiency

thin-girlEffectiveness criterion for Duromine is its ability to suppress appetite. Majority of obese people experience the reduced appetite already after the first dose of Duromine. However, some people may experience tolerability to anorexigenic effect of Duromine.

In the presence of tolerability to Duromine’ anorexigenic effect, it is impossible to control appetite and to limit the daily calorie intake. Therefore, people with diagnosed tolerability to Duromine’ anorexigenic effect should choose alternative drugs for obesity treatment.

Tolerability to anorexigenic effect most often develops in those who abused or abuse Duromine. When Duromine dosing regimen is not observed, the central nervous system stops to respond to its pharmacological activity.

Therefore, patients with a history of psychostimulant abuse do not manage to control appetite even after using the maximum daily doses of Duromine.

Other drugs used during the drug therapy of obesity may affect Duromine effectiveness. For example, after using Duromine pills and a drug from the group of phenothiazines*, Duromine efficiency significantly decreases.

Thus, before using any prescription or nonprescription drugs together with Duromine, consult a doctor or pharmacist.

*Trade names of phenothiazines: Compazine, Compro, Largactil, Levoprome, Mellaril, Modecate, Mymethazine Fortis, Nausetil, Permitil, Phenergan, Procalm, Procomp, Prolixin, Promapar, Prometh Plain, Promethegan, Remsed, Serentil, Sonazine, Stelazine, Stemetil, Stemzine, Thorazine, Trilafon, Vesprin, Zipan.

Effectiveness of anti-obesity therapy

To achieve the maximum weight loss by means of Duromine, necessarily adhere to a hypocaloric diet. Balanced diet increases the effectiveness of anti-obesity therapy and promotes the metabolism normalization.

Those who stick to the balanced, low-calorie diet, the risk of weight regain is lower than in those who do not try to normalize the eating behavior. Thus, diet should be an integral part of weight loss program.

For rapid weight loss, it is not sufficient to take Duromine appetite suppressant and to adhere to the balanced diet. Level of physical activity has the same significant influence on therapy effectiveness as diet and Duromine.

Low or moderate physical loads are recommended for obese people taking Duromine. The maximum effect is achieved when at least 15 minutes a day is devoted to physical loads.